5-azacitidine
|
antimetabolite antineoplastic agent
|
adenocarcinoma
|
tumor of glandular epithelial tissue
|
adenovirus
|
family of common human viruses that cause a variety of respiratory
and/or gastrointestinal symptoms
|
asbestos
|
group of fibrous silicate minerals used in products to provide
insulation, resistance to fire and heat, and tensile strength
|
atelectasis
|
incomplete expansion of a portion of the lung or the whole lung
|
biopsy
|
removal of a small amount of tissue for laboratory analysis
|
calcification
|
process in which tissue becomes hardened as a result of calcium
deposits
|
carboplatin
|
platinum-containing antineoplastic agent that works by cross-linking
DNA
|
cisplatin
|
platinum-containing antineoplastic agent that works by binding
to DNA of tumor cells
|
coalesce
|
to fuse or blend separate parts
|
computerized tomography (CT)
|
radiographic imaging technique that gives detailed anatomic information;
involves projection of x-ray beams through the body and cross-sectional
imaging of body planes via computer
|
contralateral
|
on the opposite side of the body relative to an organ affected
by disease
|
cyclophosphamide
|
antineoplastic alkylating agent that works by cross-linking DNA
|
cytokine
|
chemical mediator produced by a variety of cell types that regulates
immune responses and/or helps cells communicate
|
dacarbazine
|
antineoplastic alkylating agent
|
debulk
|
reduce the size or extent of tumor tissue by surgery
|
decortication
|
removal of the external layer of an organ
|
diaphragm
|
muscular, membranous partition that separates the abdominal and
thoracic cavities
|
diffuse
|
not limited or localized; widely distributed
|
diffuse malignant pleural mesothelioma
|
see malignant pleural mesothelioma
|
doxorubicin
|
anthracycline antineoplastic agent that works by inserting itself
between DNA strands and/or by alkylation
|
dyspnea
|
shortness of breath
|
epirubicin
|
anthracycline antineoplastic agent that works by inserting itself
between DNA strands and/or by alkylation
|
epithelial mesothelioma
|
cancer involving the mesothelial lining cells
|
epithelium
|
cells that make up the membranous, protective tissue that covers
most of the bodys internal and external structures
|
extrapleural pneumonectomy (EPP)
|
removal of the parietal and visceral pleurae, portions of the pericardium
and diaphragm, and the entire lung
|
gemcitabine HCl
|
taxane antineoplastic agent that exerts its effects on microtubules
|
gene therapy
|
process of inserting a new gene into an organism to replace or
repair gene function to treat a disease
|
gross pathology
|
refers to the functional and visible structural changes that result
from disease processes
|
hilar
|
pertaining to the part of an organ where nerves and vessels enter
and leave
|
histological
|
relating to the minute structure, composition, and function of
tissues
|
ifosfamide
|
antineoplastic alkylating agent that works by cross-linking DNA
|
immunohistochemical
|
refers to use of antibody-antigen reactions to locate markers specific
to certain tissues or cells
|
immunosuppressant
|
substance that reduces the effectiveness of the bodys defense
mechanisms
|
immunotherapy
|
administration of agents that induce a pro-inflammatory response
|
intercostal nerves
|
nerves that serve the muscles between the ribs
|
interferon
|
substance that helps regulate immune responses
|
interferon-gamma (IF-)
|
substance that mediates immune responses; produced by T lymphocytes
|
interleukin
|
substance that mediates immune responses
|
ipsilateral
|
on the side of the body affected by disease
|
macule
|
small spot or thickening that is different in color from the surrounding
tissue
|
magnetic resonance imaging (MRI)
|
diagnostic imaging technique using a magnetic field to provide
three-dimensional images of interior body structures
|
malaise
|
feeling of general discomfort or uneasiness; often the first indication
of an infection or other disease
|
malignant pleural mesothelioma (MPM)
|
cancer of the mesothelial membranes surrounding the lungs and lining
the thoracic cavity
|
mediastinum
|
area of the thoracic cavity between the lungs that contains the
heart
|
mesenchymal cell
|
cell that forms the supporting tissue of an organ or blood vessel
|
mesothelial cell
|
flat cell that forms the superficial layer of membranes lining
the thoracic and abdominal cavities
|
mesothelium
|
continuous layer of mesothelial cells that lines the pleurae, pericardium,
and peritoneum
|
metastases (s., metastasis)
|
spread of disease from one part of the body to remote sites
|
methotrexate
|
antimetabolite antineoplastic agent that works by interfering with
normal synthesis of DNA
|
mitomycin C
|
antimetabolite antineoplastic agent that works by interfering with
normal DNA synthesis
|
mixed type mesothelioma
|
cancer involving the epithelial and mesenchymal cells of the mesothelium
|
multi-targeted antifolate (MTA)
|
antineoplastic agent that inhibits the action of many enzymes
|
nodule
|
small, solid, slightly raised area
|
p-30 protein
|
antineoplastic agent that may inhibit cancer cell growth
|
paclitaxel
|
taxane antineoplastic agent that exerts its effects on microtubules
|
palliative
|
refers to an intervention that controls, reduces, or prevents symptoms
but is not intended to cure the underlying disease
|
palpable
|
perceptible to touch
|
parietal pleura
|
portion of the pleura that lines the thoracic cavity and upper
surface of the diaphragm
|
pathogenesis
|
events and reactions occurring in the development of a disease
|
pericardial mesothelioma
|
cancer of the mesothelial membrane covering the heart
|
pericardium
|
membrane that covers the heart
|
peritoneal mesothelioma
|
cancer of the mesothelial membrane lining the abdominal cavity
|
peritoneum
|
membrane that covers the abdominal cavity and its organs
|
photodynamic therapy
|
systemic administration of light-sensitive molecules that concentrate
in malignant cells and produce compounds toxic to the cells upon
exposure to light
|
photosensitizer
|
compound that causes a tissue or cell to be affected by light
|
pirarubicin
|
anthracycline antineoplastic agent; also known as THF-adriamycin
|
pleurae (s., pleura)
|
membranes that cover the lungs and line the chest cavity
|
pleural effusion
|
accumulation of excess fluid in the space between the pleurae
|
pleural mesothelioma
|
cancer of the membranes that cover the lungs and chest cavity
|
pleural space
|
cavity between the parietal and visceral pleurae
|
pleurectomy
|
removal of the parietal and visceral pleurae
|
pleuroscopy
|
examination of the pleural space with an endoscope inserted into
a small incision in the chest wall
|
radiosensitive
|
readily affected by radiation
|
raltitrexed
|
antineoplastic agent that inhibits tumor cells from multiplying
by interfering with cells ability to make DNA
|
resectable
|
amenable to resection (surgical removal of a diseased portion of
a tissue)
|
sarcomatous mesothelioma
|
type of mesothelioma arising from the mesenchymal cells of the
mesothelium
|
silicate
|
refers to a compound that occurs in many minerals and rocks, eg,
quartz, sand, agate
|
simian virus 40 (SV40)
|
type of virus commonly found in monkeys; may produce infections
in humans and malignancies in human cell cultures
|
subcarinal
|
denotes lymph nodes located below the bony ridge of the esophagus
|
thoracentesis
|
surgical puncture of the chest wall to aspirate fluid from the
pleural space
|
thoracic
|
relating to the chest
|
thoracoscopy
|
see pleuroscopy
|
tuberculous pleuritis
|
inflammation of the pleura associated with tuberculosis
|
vincristine
|
vinca alkaloid antineoplastic agent
|
visceral pleura
|
portion of the pleura that covers the external surface of the lungs
|